R&D FOR BEHAVIOR CHANGE Collaborative development to automate and assess digital health interventions.


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Automated Telecommunication-Based Reminders and Adherence With Once-Daily Glaucoma Medication Dosing

  • February 2015

The Automated Dosing Reminder Study

Michael V. Boland, MD, PhD1,2; Dolly S. Chang, MD, PhD1,3; Travis Frazier, MD4; Ryan Plyler, BS5; Joan L. Jefferys, ScM3; David S. Friedman, MD, MPH, PhD1,3

JAMA Ophthalmol. July 2014, Vol 132, No. 7


Importance Topical glaucoma medications lower intraocular pressure and alter the course of the disease. Because adherence with glaucoma medications is a known problem, interventions are needed to help those patients who do not take their medications as prescribed.

Objective To assess the ability of an automated telecommunication-based intervention to improve adherence with glaucoma medications.

Design, Setting, and Participants We performed a prospective cohort study of medication adherence, followed by a randomized intervention for those found to be nonadherent, of individuals recruited from a university-based glaucoma subspecialty clinic. A total of 491 participants were enrolled in the initial assessment of adherence. Of those, 70 were nonadherent with their medications after 3 months of electronic monitoring and randomized to intervention and control groups.


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