Articles, Whitepapers, Videos, Publications.


Please feel free to browse a our library of resources regarding innovations in Patient Adherence.


JmHealth Path to Digital Health Nirvana

Digital health is turning into one of those catch-all terms that people use to describe everything from electronic medical records to smartphone apps to wearable devices.  While I’m happy that the world is starting to pay attention, I’ve noticed a worrying trend.  We have a multitude of devices creating tremendous amounts of patient data, but very few tools/devices that make intelligent use of that data.   In another way, it’s like we have more and more gadgets to tell us we are unhealthy without giving using any meaningful advice on how to become healthier.  This intelligent use of data is exactly the topic of my latest piece for the Journal of mHealth.  In it, I talk about these disparate sources of patient data and how using this data effectively can create substantial value for patients and healthcare stakeholders.  We’ll see what the future holds, but betting is not on devices, but the actioning of data that changes the healthcare landscape.

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Although I don’t know him personally Joseph Kvedar is someone who I look up to, he’s been at the forefront of digital health for many years and a leader in the identification, validation and application of digital health. In this paper,  Joseph Kvedar, Alexander Fogel, Eric Elenko & Daphne Zohar describe key advances, the marketplace and the opportunity for digital medicine in chronic disease. In the publication, the group outline several key advances in digital health, monitoring, adherence and behavior change. A focus on evidence-based interventions shows that there is a shift-change from concept to reality in a number of different digital health domains. The article aptly moves digital health into the mainstream as a significant way of augmenting and helping move a system focussed on acute care to one to help manage a continuum of care over time. Challenges exist in security, privacy, validation, application and reimbursement but they are outnumbered by the opportunities.

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What mHealth Professionals Keep Asking: Don’t Patients Want to Get Better?

December 20, 2012

Amos Amos Adler, M.Sc. is the Founder & President of MEMOTEXT

Combating the barriers to patient adherence requires a disciplined, and focused and cost-effective approach. This approach must encompass all the stakeholders in the healthcare equation including payors, pharmas and providers. By looking at patient behaviors, motivations and understanding, we can effect change at the patient level. On a systemic level; Payors can save on critical care costs, pharmaceutical manufacturers can stabilize revenue and the system can benefit from less drain on the economy and overall costs. Everyone stands to benefit from increased compliance, most of all…the patient.


Evidence-based mHealth Adherence-related Interventions

Miki Peer Medical Science Liaison, MEMOTEXT                           Journal for Patient Compliance,       Volume 3 Issue 1 2013

Adherence is Transdisciplinary, Perhaps Even its Own ‘Discipline’

The issue of patient adherence is complex and involves interacting dimensions of patient-related factors, social/economic factors, condition-related factors, therapy related factors, and health system/healthcare team factors1. In other words, the nature of the adherence beast is multi-faceted and inherently interdisciplinary. Expert advice informing best practices to improve
patient adherence is needed from healthcare-related clinicians (doctors, nurses, pharmacists), mental health experts (psychologists, psychiatrists), sociologists, social workers, epidemiologists, health-related researchers, and policy-makers (among others). A more appropriate term for how adherence should be properly viewed then may be transdiciplinary. That is, adherence requires a holistic approach, one that seeks to integrate knowledge from all related disciplines into a coherent whole.


Click Bait for Your Health: How a Toronto Startup Uses Digital Engagement to Increase Medication Adherence

Amos Adler Founder and President, MEMOTEXT                                                                                Date Published November 17, 2015

The MaRS Centre for Impact Investing and the Royal Bank of Canada (RBC) are proud to announce the 2015 RBC Impact Entrepreneurs. The Entrepreneurs were showcased at the 8th annual Social Finance Forum.

Using digital engagement to increase medication adherence is our novel solution to a complex problem. With non-adherence caused by multiple factors unique to each individual patient, a-one-size-fits-all-solution can’t work and won’t work. Instead, at MEMOTEXT we personalize each patient’s support program. By encouraging patient input adapting to the changes in their mood and lifestyle we can develop an adherence and support program that works best for them!


Impact Investing Moves from the Margins to the Mainstream

Muska Ulhaq Program Coordinator, MaRS Centre for Impact Investing and Interim- Managing Editor of SocialFinance.ca

Date Published October 26, 2015

Today, we know that the scale of our global problems far exceed the resources currently allocated to solve them. A new breed of investor is now emerging—one that is not only interested in financial returns but also in generating social and environmental value. By mobilizing private capital, impact investing promises to unlock new capital sources to do good.


8 social impact startups you need to know
How cute cat photos may change the way you take care of your health

By    Oct 6, 2015

We’ve all had that “Oops!” moment when we realize we missed a dose of medication. Forgetting to take a birth control pill can be a minor nuisance (albeit one that occasionally results in a baby.) For more serious illnesses, though, forgetting meds can cause serious health complications.

One Canadian company thinks they have a solution: cute cat photos.


Can cute cat texts motivate patients to take their medication?

on October 6th, 2015

The right kind of motivation is key when you have a difficult or mundane task at hand. For example, when I wanted to learn Spanish, I tried several top-rated, online language tools to no avail because they felt like work to me. Then, half as a joke, my boyfriend suggested an app that associates Spanish phrases with images of cats acting out the meaning of the words. The app was so silly I used it often, and — to our amazement — it actually worked.



One company hopes cute cat pictures will convince you to take your medicine

By STEPHANIE BAUM Oct 5, 2015 at 7:56 AM

black cat meme 2

Memotext is trying a different approach as part of its push to trigger a conversation to get patients to change behavior: cute cat images. It is part of a mobile chat bot to automate conversations to improve adherence and fits into a broader program

“We’re not only asking whether you did something, but why did you do it,” Memotext Founder and President Amos Adler said in an interview. “It is mostly about figuring out how to send content to people in the context of their health.”


Announcing Impact8’s 4th Cohort

Kevin Taylor  Senior Associate, MaRS Centre for Impact Investing                                                 Date Published September 22, 2015


Initially launched in 2013, Impact8 helps to close the gap between growth-stage impact based ventures and investors interested in opportunities to fund business with a social benefit. By providing mentorship and targeted workshops, Impact8 increases the pipeline of fundable business, introduces impact start-ups to the fundraising process, and connects social entrepreneurs to investors, partners and experts in the field of social innovation.


Will Arizona’s Medicaid beneficiaries use smartphone apps?

By Jonah Comstock | Aug 5, 2015

Arizona Governor Doug Ducey carved out a place for mobile health in his plan for the state’s new Medicaid plan this week, but some critics think the initiative could miss the mark for a low-income population less likely to have smartphones.

Arizona’s Medicaid system, the Arizona Healthcare Cost Containment System (AHCCCS), is a managed care system that operates on a special waiver from the federal government. That waiver is set to expire next September, and Ducey is using that expiration as an opportunity to make changes to the system that he hopes will cut costs by empowering Medicaid users and helping them get back to work. The changes, a plan called “Choice, Accountability, Responsibility and Engagement” (CARE), include health savings accounts, strategic co-pays, and wellness incentives for Medicaid enrollees.


MEMOTEXT Corporation et STI Technologies forment une alliance stratégique pour dynamiser l’observance thérapeutique au Canada

Les deux entreprises associeront les communications numériques et des solutions validées axées sur des programmes de cartes dans l’objectif d’offrir une approche intégrée visant l’amélioration de l’observance des patients envers leurs traitements médicamenteux

TORONTO, le 28 avril 2015 /CNW/ – MEMOTEXT Corporation a annoncé aujourd’hui la formation d’une alliance stratégique avec STI Technologies Limited dans le but d’offrir une plateforme de communication numérique de pointe associée à la technologie des cartes intelligentes afin d’améliorer l’observance thérapeutique.

Les deux entreprises canadiennes collaborent pour associer leurs technologies respectives afin de résoudre un problème très coûteux dans le domaine des soins de santé. Bien que leurs opérations se situent dans des sphères différentes de l’industrie des soins de santé, STI et MEMOTEXT utilisent des méthodologies appuyées par des données probantes et possèdent des solutions validées qui se complètent. Selon un article publié dans JAMA, il a été démontré que les solutions numériques d’observance validées en clinique de MEMOTEXT augmentent l’observance thérapeutique des patients de 31,4 %.


MEMOTEXT Corp. and STI Technologies form Strategic Alliance to Supercharge Patient Adherence in Canada

Companies will combine digital communications and card based validated solutions, to provide integrated approach to increasing patient medication adherence

TORONTO, April 28, 2015 /CNW/ – MEMOTEXT Corp. announces today the formation of a strategic alliance with STI Technologies Limited to provide state-of-the art digital communications platform and smart-card technology, to improve patient compliance with medications.

The two Canadian companies are collaborating to integrate their technologies to solve a very costly healthcare problem. Despite operating in different spaces of the healthcare industry, both companies have evidence-based methodologies and validated solutions that complement each other. MEMOTEXT’s JAMA published clinically validated digital adherence solutions have been shown to increase patient adherence by 31.4%.


PerformRx Launches Personalized Digital Mobile Platform to Improve Medication Adherence for Asthma Patients



FOR IMMEDIATE RELEASE                                                                                                                  Contact: Michelle Davidson

February 24, 2015                                                                                                                                     215-208-9816



PerformRx Launches Personalized Digital Mobile Platform to Improve

Medication Adherence for Asthma Patients


HealthNHand helps health plans extend care management with

air quality and behavior change interventions


Philadelphia, PA – PerformRx, (www.performrx.com), a URAC-accredited, full service pharmacy benefits manager with industry-leading clinical programs, announced today the launch of HealthNHand, a personalized digital mobile platform aimed at improving medication adherence. HealthNHand will be initially offered to members of AmeriHealth District of Columbia, the largest Medicaid managed care organization in the District.


HealthNHand, developed by MEMOTEXT, a health care technology company, is designed to improve adherence to treatment regimens. Participants receive reminders to take their asthma medications and complete questionnaires about their health status via interactive voice response, short message service (SMS) or email. HealthNHand’s personalized information, targeted support and daily air quality forecasts, generated for each user based on results from the questionnaires, help asthma patients become more aware and engaged in their own self-care.



Made-in-Ontario healthcare innovations expanding south

by Lara Torvi – 20 Feb 2015

Three MaRS health ventures announced expansion in the US this week. The technologies they offer range from personalized disease prevention and medication monitoring to real-time surveillance technology that controls the spread of hospital-acquired infections.

Their push into the US market is a sign of the continued growth of Ontario-based health and life sciences companies that are developing new tools that not only prevent illness, but also help speed up healing. Health and life sciences companies in Ontario generate revenues of $39 billion a year, with almost $6 billion generated by exports to countries all over the world. With annual healthcare spending in the US reaching $3.8 trillion in 2014, these solutions are critical to the future of our health systems.


MaRS’ new District 20 means business


“This is a great space. We lobbied hard to get here.”

I’m sitting across from Eric Riz, founder of Empty Cubicle, in the boardroom of MaRS’ new co-working space, District 20. A 6,000 square foot section of the MaRS Heritage Building (in what I’m told is rumoured to be the old Toronto General morgue), District 20 blends 20th century facilities with 21st century function in a way most have come to expect from the innovation hub. The sandy-bricked space is filled with colour-coded, pod-like offices; minimalist yet comfortable furniture lines the hallways and common areas, which feature private booths for phone calls or a quick break-out meeting. The space feels warm and professional.

But Riz isn’t talking about the space as an office, or at least not entirely. He’s talking about it as an extension of MaRS. MaRS has a mixed history convincing startups to take residency in its space. Riz is frank in his contrarian opinion.


Automated Telecommunication-Based Reminders and Adherence With Once-Daily Glaucoma Medication Dosing

The Automated Dosing Reminder Study

Michael V. Boland, MD, PhD1,2; Dolly S. Chang, MD, PhD1,3; Travis Frazier, MD4; Ryan Plyler, BS5; Joan L. Jefferys, ScM3; David S. Friedman, MD, MPH, PhD1,3

JAMA Ophthalmol. July 2014, Vol 132, No. 7


Importance Topical glaucoma medications lower intraocular pressure and alter the course of the disease. Because adherence with glaucoma medications is a known problem, interventions are needed to help those patients who do not take their medications as prescribed.

Objective To assess the ability of an automated telecommunication-based intervention to improve adherence with glaucoma medications.

Design, Setting, and Participants We performed a prospective cohort study of medication adherence, followed by a randomized intervention for those found to be nonadherent, of individuals recruited from a university-based glaucoma subspecialty clinic. A total of 491 participants were enrolled in the initial assessment of adherence. Of those, 70 were nonadherent with their medications after 3 months of electronic monitoring and randomized to intervention and control groups.


Electronic Reminders Can Improve Glaucoma Patients’ Drug Adherence

May 22, 2014 By Gabriel Miller

NEW YORK – A considerable proportion of glaucoma patients don’t take their medicine as prescribed, but electronic monitoring and reminders can boost adherence, according to a pair of reports on a new study.

“We now have two randomized trials — including this one — that have demonstrated an approximately 20% increase in adherence with glaucoma medications in a group shown to be non-adherent,” Dr. Michael Boland, lead author of both papers, told Reuters Health by email.

“There are no other interventions that have shown this level of improvement in this group,” said Dr. Boland from Johns Hopkins University in Baltimore, Maryland.

Both papers were published online May 15 in JAMA Ophthalmology.



How One Healthcare Entrepreneur Created His Own Access

Christina Hernandez Sherwood on May 20, 2014.

Like many healthcare entrepreneurs, Amos Adler of MEMOTEXT found it difficult to access the stakeholders who could help to make his patient adherence company a success. The challenge, he said, is that access is dependent on how a startup can align with the business model of the stakeholders involved. “Can you get into their business model,” he said, “and can you get into the clinical workflow?”

To get around that, Adler and MEMOTEXT have found their own solution. “We’re in the midst of building out what we call ‘the alliance for adherence,'” he said. The alliance, Adler said, consists of a group of stakeholders who have access to patients and a common interest in patient adherence.

Here are other entrepreneurial insights from Adler:


Canadian University Develops New Program To Help Educate Expectant Moms

by Jennifer Corter, Apr. 27, 2014

In this ever-changing world of technology, it is amazing how quickly things change. For example, for a while now, when women were pregnant, they had the option of attending classes focused on prenatal education over the course of their pregnancies. But unfortunately, not everyone can attend these classes due to prior commitments, medical reasons or a variety of other reasons. They would end up missing out on these important educational experiences. But researchers at the University of British Columbia are aiming to change that through the use of educational text messages for these women.

The SmartMom Canada program was created to meet the needs in British Columbia’s northern health region. Researchers’ aim is to have women in that area try out the program, along with women in the Fraser Valley Health region. Patti Janssen, professor at UBC’s School of Population and Public Health is spearheading the initiative, along with the university’s Child and Family Research Institute.


UBC project hopes to deliver prenatal education via text

But SmartMom Canada initiative still needs to raise nearly $100,000


Researchers at the University of B.C. are extending the growing trend of digital health to the womb with a project aimed at delivering prenatal education by text to moms-to-be who can’t attend classes.

The program, SmartMom Canada, was created to meet a need in B.C.’s northern health region and will be piloted there and in the Fraser Valley Health region. Professor Patti Janssen of UBC’s School of Population and Public Health is leading the initiative in conjunction with the university’s Child and Family Research Institute.


PerformRx Goes Behind the Scenes to Get a Better Picture of Patient Adherence

By Lauren Flynn Kelly, Editor Drug Benefit News, January 24, 2014 Volume 15 Issue 2

Insurers, PBMs and pharmacies have myriad ways to make sure patients physically obtain their medications, from monitoring patients at the point of sale to automatic mail-order refills. But how can anyone be sure what happens once the patient is at home with that medication?

“That’s the piece that has always been missing in medication adherence,” observes Mesfin Tegenu, R.Ph., president of PerformRx, LLC, a wholly owned subsidiary of the AmeriHealth Caritas Family of Companies. And adherence is especially important for those “who are on multiple medications, who are confused about how many pills to take or when to take them,” he asserts. “So our goal is to see how we can help patients comply and how we can make sure that they take their medications.”


PM360 Presents Novel Patient-Centric Strategies

360 Staff, May 21st, 2013

Patient Centricity. You have probably heard that phrase a million times this year alone. After all, it is one of the biggest buzzwords of 2013. But there is a reason for that. Pharma needs to find a way to better reach and engage with patients—and this goes beyond ads that get them to ask their doctors about a specific brand. This is about better understanding patients and learning how pharma can better serve them. This is about improving patient adherence and outcomes.

The good news is that the industry gets that. We asked our readers for innovative patient-centric initiatives and strategies and our inboxes were flooded with responses. Of course, pharma is probably well aware that medical non-adherence costs the industry billions of dollars a year. (An estimated loss of $564 billion globally according to Capgemini Consulting.) But the industry also cares about giving patients a voice, providing them with tools that can help them stay on medication and creating an environment where they can connect with others like themselves.


A Spoonful of Sugar: Developing a Medication – Reminder App

Sticking to a health regimen means remembering to take prescribed medications. But studies of medication adherence show that patients often fail to stay with the program. A prescription drug survey published by the National Community Pharmacists Association (NCPA) revealed that nearly 50 percent of consumers said they forgot to take a prescribed medication, while 24 percent said they took less than the recommended dosage.

Against this backdrop, MEMOTEXT, a company focused on medication- and treatment-compliance programs, offers a medication-adherence service that issues reminders to a patient’s mobile phone, tablet, PC or landline. The service is offered in more than 26 countries.

We spoke to Amos Adler, founder and president of MEMOTEXT, about how the system works and what it was like developing for the growing healthcare app market.

Read more: A Spoonful of Sugar: Developing a Medication-Reminder App http://www.digitalinnovationgazette.com/blog/medication_reminder_healthcare_app_market/index.html#ixzz3GtLLyMGh
Follow us: @DIGMobileDev on Twitter | digitalinnovationgazette on Facebook


“Everyone is Different and People Change. Our Technology Should Know as Much and Adapt with us. MEMOTEXT Personalizes your Health Interaction Experience.”

Dec 19th, 2012. By Amos Adler

Prior to founding MEMOTEXT, Amos Adler was a business solutions architect for the Bell Canada Enterprises (BCE) group of Companies. While at Bell Canada, Bell Mobility and other operating entities, he managed the design, implementation and integration of various CRM, ERP, Voice/Speech Recognition, IVR and web 2.0 and CTI – legacy system integration initiatives.

MEMOTEXT is a professional services firm and SaaS engine that focusses solely on medication and treatment compliance programs for healthcare stakeholders. MEMOTEXT® specializes in evidence based personalization of patient compliance interventions.

With a proprietary methodology and The MEMOTEXT Personologic™ inference engine, we integrate behavior modification, education and real-time support into the everyday lives of patients using everyday technologies patients already have. Our ability to learn and remember previously reported knowledge, intentions and behaviors allows us to adapt communications to changing attitudes, knowledge levels and circumstances of each patient using best of breed, secure mobile, speech and social medication adherence tools.


MedCity News: America, the Land of mhealth Opportunity

 4:14 pm by Stephanie Baum.

The American mobile health app landscape is perceived as an open market for innovation. Yet the lack of any particular oversight or regulation specific to mobile health means there is a wide variety of apps on the market that swing from FDA approved medical devices to apps that make unproven medical claims.

But as so often happens in the early days of many industries, the ones that distinguish themselves by filling an unmet or inadequately addressed need or can be adapted to disparate systems, find a home and are widely used.



Social Support and Patient Adherence

Social Support and Patient Adherence

How social relationships influence medication compliance
This week’s focus is on social support – an area that has received extensive attention in health research.  Social support is what arises from our social relationships; it is the care and assistance we receive from others, especially as it relates to physical and mental health.  With such a broad definition, social support has been shown to affect nearly every health outcome studied.  There are differences in the extent of that impact, however, depending on the specific health issue or behavior, how social support is defined and measured, and factors related to the individuals involved.  As an introduction to this topic, we’ll focus on the different types of social support and the factors that most commonly determine how helpful it is in managing health and its effect on patient adherence.

Social support encompasses a range of behaviors and these are often categorized as:  i) emotional support, ii) instrumental (or practical) support, iii) informational support, and iv) appraisal.  Emotional support includes care, empathy, companionship, and trust whileinstrumental support includes tangible or practical aid (such as providing money or transportation to a doctor’s appointment for example).  Informational support includes advice, suggestions and other forms of education/knowledge about health while appraisal provides feedback and affirmation that can be used for self-evaluation of health behaviors and/or beliefs.  A single source of social support may provide multiple kinds of social support (e.g., a friend who listens to your struggles with healthy eating and recommends a good cookbook) or only one kind of social support (e.g., a pharmacist who tells you how to properly take your medications).

In health research social support is often measured as perceived social support (how much support an individual thinks or feels s/he is getting), actual/received social support (how many times an individual actually received some form of assistance, for example on a weekly basis), and/orsocial integration (the number of persons available to provide support).

The most important factors related to the individuals involved are: i) nature of the relationship(spouse, friend, clinician), ii) proximity and/or accessibility, iii) knowledge/experience with respect to the health problem or health behavior.

Of course there are also broader aspects to how social relationships influence health including social influence, social undermining, and social comparison.  This highlights an important point about social support, namely that it can also exert negative influences (aside from positive ones).  For example, long-term caregiving can be stressful and, eventually, taxing on the caregiver’s own health.  Similarly, a miss-match between the type of support desired/needed and the type received can be discouraging (or even damaging) to the person seeking support.

Strong levels of social support are linked with lower levels of stress, greater levels of happiness, and a longer life.  It is worthwhile to take a few moments to think about your current social network – in what ways is it is helpful (or harmful) to your health?  Next week we will provide a specific exercise you can do to increase the level of social support you receive from your own social network.

This entry was posted in MEMOTEXT Patient Adherence Team Blog. Bookmark the permalink.

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10 Questions to Ask Before Determining Your Target Market


“We often overestimate the market size, and in many cases there may not be one at all,” says Robert Hisrich, director of the Walker Center for Global Entrepreneurship at the Thunderbird School of Global Management in Glendale, Ariz.

Here are 10 questions that can help you determine whether you have a target market and what it is:


Automated Med Reminders Boost Adherence

June 8th, 2011.

Glaucoma, the world’s second leading cause of blindness, has a number of effective therapies to help those afflicted. Despite these solutions, non-adherence rates for those treatments are reported to be between thirty-seven and fifty-nine percent. Luckily, mobile health professionals are working on ways to solve this issue. One such company, Memotext, has been developing adherence technologies and may have proof that its solution will improve those statistics.

Memotext and Microsoft’s recent study (funded by Microsoft and conducted by Johns Hopkins University) measured the efficacy of using the Memotext adherence solution combined with Microsoft’s personal health tracking platform HealthVault. Patients received some combination of text message reminders and IVR messages to remind them about their medication regimen.




Automated Telecommunication-Based Reminders and Adherence With Once-Daily Glaucoma Medication Dosing

July 2014, Vol. 132, N0.7

Importance  Topical glaucoma medications lower intraocular pressure and alter the course of the disease. Because adherence with glaucoma medications is a known problem, interventions are needed to help those patients who do not take their medications as prescribed.

Objective  To assess the ability of an automated telecommunication-based intervention to improve adherence with glaucoma medications.

Design, Setting, and Participants  We performed a prospective cohort study of medication adherence, followed by a randomized intervention for those found to be nonadherent, of individuals recruited from a university-based glaucoma subspecialty clinic. A total of 491 participants were enrolled in the initial assessment of adherence. Of those, 70 were nonadherent with their medications after 3 months of electronic monitoring and randomized to intervention and control groups.



Meet the Amazing Healthcare Startups on Display at MedCity CONVERGE

 3:36 pm by Ryan Amin.

A pill bottle that informs doctors of medicine intake. Cloud-based software improving patient and doctor communication. Ice packs that instantly take away pain.

Those are just a few of the products that will be on display by nearly two dozen early-stage companies in the Startup Showcase at MedCity CONVERGE, MedCityNews.com’s executive summit on innovation and healthcare on July 9-10 in Philadelphia.


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